If you tell me more about what happens when you click the file, I can narrow this down: Any specific error codes (like 0xc000007b)?
Alternatively, disable Controlled Folder Access in Windows Security under Virus & Threat Protection settings. Check for Multiple Monitors
Sometimes, security software flags the settings tool as a "false positive" and kills the process before it can open. Temporarily disable your real-time antivirus protection. pes 2021 settingsexe not opening new
Check the box for Run this program in compatibility mode for and select Windows 8. Click Apply and try opening the file again. Update DirectX and .NET Framework
Try moving your Steam library to a different drive (e.g., D:\Games). If you tell me more about what happens
If you see it in the taskbar but not on screen, hold the Windows Key + Shift + Left/Right Arrow to snap it back into your current view.
If you use a multi-monitor setup or recently disconnected a screen, the settings window might be opening "off-screen." Launch settings.exe. Temporarily disable your real-time antivirus protection
Check your Quarantine folder to see if settings.exe was moved there. Move the Folder Out of System Directories
If you are trying to optimize your graphics or change your controller mapping, it is incredibly frustrating when the settings.exe file for PES 2021 simply refuses to launch. This is a common issue with the PC version of eFootball PES 2021 Season Update, often caused by missing software components, administrative restrictions, or hardware detection errors.
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